Endoplasmic reticulum and Golgi stress in microcephaly
نویسندگان
چکیده
منابع مشابه
Endoplasmic reticulum-Golgi intermediate compartment protein 3 knockdown suppresses lung cancer through endoplasmic reticulum stress-induced autophagy
Trafficking from the endoplasmic reticulum (ER) to the Golgi apparatus is elevated in cancer cells. Therefore, proteins of the ER-Golgi intermediate compartment (ERGIC) attract significant attention as targets for cancer treatment. Enhanced cancer cell growth and epithelial-mesenchymal transition by ERGICs correlates with poor-prognosis of lung cancer. This prompted us to assess whether knockdo...
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Cellular homeostasis is supported by a symphonic balancing act involving protein synthesis, folding, modification, trafficking and degradation. In eukaryotic cells the endoplasmic reticulum (ER) is a specialized organelle that is the central site of synthesis and folding of secretory, membrane and a number of organelletargeted proteins. Correct folding and post-translational modifications of th...
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ژورنال
عنوان ژورنال: Cell Stress
سال: 2019
ISSN: 2523-0204
DOI: 10.15698/cst2019.12.206